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1.

LAG3 associates with TCR-CD3 complexes and suppresses signaling by driving co-receptor-Lck dissociation.

Guy, Clifford; Mitrea, Diana M; Chou, Po-Chien; Temirov, Jamshid; Vignali, Kate M; Liu, Xueyan; Zhang, Hui; Kriwacki, Richard; Bruchez, Marcel P; Watkins, Simon C; Workman, Creg J; Vignali, Dario A A.

Nat Immunol ; 23(5): 757-767, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35437325

2.

Coexisting Liquid Phases Underlie Nucleolar Subcompartments.

Feric, Marina; Vaidya, Nilesh; Harmon, Tyler S; Mitrea, Diana M; Zhu, Lian; Richardson, Tiffany M; Kriwacki, Richard W; Pappu, Rohit V; Brangwynne, Clifford P.

Cell ; 165(7): 1686-1697, 2016 Jun 16.

Artículo en Inglés | MEDLINE | ID: mdl-27212236

3.

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.

Lee, Kyung-Ha; Zhang, Peipei; Kim, Hong Joo; Mitrea, Diana M; Sarkar, Mohona; Freibaum, Brian D; Cika, Jaclyn; Coughlin, Maura; Messing, James; Molliex, Amandine; Maxwell, Brian A; Kim, Nam Chul; Temirov, Jamshid; Moore, Jennifer; Kolaitis, Regina-Maria; Shaw, Timothy I; Bai, Bing; Peng, Junmin; Kriwacki, Richard W; Taylor, J Paul.

Cell ; 167(3): 774-788.e17, 2016 Oct 20.

Artículo en Inglés | MEDLINE | ID: mdl-27768896

4.

C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function.

White, Michael R; Mitrea, Diana M; Zhang, Peipei; Stanley, Christopher B; Cassidy, Devon E; Nourse, Amanda; Phillips, Aaron H; Tolbert, Michele; Taylor, J Paul; Kriwacki, Richard W.

Mol Cell ; 74(4): 713-728.e6, 2019 05 16.

Artículo en Inglés | MEDLINE | ID: mdl-30981631

5.

CD-CODE: crowdsourcing condensate database and encyclopedia.

Rostam, Nadia; Ghosh, Soumyadeep; Chow, Chi Fung Willis; Hadarovich, Anna; Landerer, Cedric; Ghosh, Rajat; Moon, HongKee; Hersemann, Lena; Mitrea, Diana M; Klein, Isaac A; Hyman, Anthony A; Toth-Petroczy, Agnes.

Nat Methods ; 20(5): 673-676, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-37024650

6.

Composition-dependent thermodynamics of intracellular phase separation.

Riback, Joshua A; Zhu, Lian; Ferrolino, Mylene C; Tolbert, Michele; Mitrea, Diana M; Sanders, David W; Wei, Ming-Tzo; Kriwacki, Richard W; Brangwynne, Clifford P.

Nature ; 581(7807): 209-214, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32405004

7.

Flipping the switch.

Rizzolo, Kamran; Mitrea, Diana M.

Nat Chem Biol ; 18(10): 1041-1042, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-35864334

8.

Structural polymorphism in the N-terminal oligomerization domain of NPM1.

Mitrea, Diana M; Grace, Christy R; Buljan, Marija; Yun, Mi-Kyung; Pytel, Nicholas J; Satumba, John; Nourse, Amanda; Park, Cheon-Gil; Madan Babu, M; White, Stephen W; Kriwacki, Richard W.

Proc Natl Acad Sci U S A ; 111(12): 4466-71, 2014 Mar 25.

Artículo en Inglés | MEDLINE | ID: mdl-24616519

9.

Phase separation in biology; functional organization of a higher order.

Mitrea, Diana M; Kriwacki, Richard W.

Cell Commun Signal ; 14: 1, 2016 Jan 05.

Artículo en Inglés | MEDLINE | ID: mdl-26727894

10.

Asymmetric Modulation of Protein Order-Disorder Transitions by Phosphorylation and Partner Binding.

Banerjee, Priya R; Mitrea, Diana M; Kriwacki, Richard W; Deniz, Ashok A.

Angew Chem Int Ed Engl ; 55(5): 1675-9, 2016 Jan 26.

Artículo en Inglés | MEDLINE | ID: mdl-26679013

11.

Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein.

Mann, Beth; Thornton, Justin; Heath, Richard; Wade, Kristin R; Tweten, Rodney K; Gao, Geli; El Kasmi, Karim; Jordan, John B; Mitrea, Diana M; Kriwacki, Richard; Maisonneuve, Jeff; Alderson, Mark; Tuomanen, Elaine I.

J Infect Dis ; 209(7): 1116-25, 2014 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-24041791

12.

Biomolecular Condensates as Novel Antiviral Targets.

Martin, Erik W; Iserman, Christiane; Olety, Balaji; Mitrea, Diana M; Klein, Isaac A.

J Mol Biol ; 436(4): 168380, 2024 02 15.

Artículo en Inglés | MEDLINE | ID: mdl-38061626

13.

Biomolecular condensates form spatially inhomogeneous network fluids.

Dar, Furqan; Cohen, Samuel R; Mitrea, Diana M; Phillips, Aaron H; Nagy, Gergely; Leite, Wellington C; Stanley, Christopher B; Choi, Jeong-Mo; Kriwacki, Richard W; Pappu, Rohit V.

bioRxiv ; 2024 Feb 11.

Artículo en Inglés | MEDLINE | ID: mdl-37873180

14.

Biomolecular condensates form spatially inhomogeneous network fluids.

Dar, Furqan; Cohen, Samuel R; Mitrea, Diana M; Phillips, Aaron H; Nagy, Gergely; Leite, Wellington C; Stanley, Christopher B; Choi, Jeong-Mo; Kriwacki, Richard W; Pappu, Rohit V.

Nat Commun ; 15(1): 3413, 2024 Apr 22.

Artículo en Inglés | MEDLINE | ID: mdl-38649740

15.

Engineering an artificial zymogen by alternate frame protein folding.

Mitrea, Diana M; Parsons, Lee S; Loh, Stewart N.

Proc Natl Acad Sci U S A ; 107(7): 2824-9, 2010 Feb 16.

Artículo en Inglés | MEDLINE | ID: mdl-20133757

16.

Biomolecular condensates form spatially inhomogeneous network fluids.

Dar, Furqan; Cohen, Samuel R; Mitrea, Diana M; Phillips, Aaron H; Nagy, Gergely; Leite, Wellington C; Stanley, Christopher B; Choi, Jeong-Mo; Kriwacki, Richard W; Pappu, Rohit V.

Res Sq ; 2023 Oct 18.

Artículo en Inglés | MEDLINE | ID: mdl-37886520

17.

Phase Separation in Biology and Disease; Current Perspectives and Open Questions.

Boeynaems, Steven; Chong, Shasha; Gsponer, Jörg; Holt, Liam; Milovanovic, Dragomir; Mitrea, Diana M; Mueller-Cajar, Oliver; Portz, Bede; Reilly, John F; Reinkemeier, Christopher D; Sabari, Benjamin R; Sanulli, Serena; Shorter, James; Sontag, Emily; Strader, Lucia; Stachowiak, Jeanne; Weber, Stephanie C; White, Michael; Zhang, Huaiying; Zweckstetter, Markus; Elbaum-Garfinkle, Shana; Kriwacki, Richard.

J Mol Biol ; 435(5): 167971, 2023 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-36690068

18.

Defining the condensate landscape of fusion oncoproteins.

Tripathi, Swarnendu; Shirnekhi, Hazheen K; Gorman, Scott D; Chandra, Bappaditya; Baggett, David W; Park, Cheon-Gil; Somjee, Ramiz; Lang, Benjamin; Hosseini, Seyed Mohammad Hadi; Pioso, Brittany J; Li, Yongsheng; Iacobucci, Ilaria; Gao, Qingsong; Edmonson, Michael N; Rice, Stephen V; Zhou, Xin; Bollinger, John; Mitrea, Diana M; White, Michael R; McGrail, Daniel J; Jarosz, Daniel F; Yi, S Stephen; Babu, M Madan; Mullighan, Charles G; Zhang, Jinghui; Sahni, Nidhi; Kriwacki, Richard W.

Nat Commun ; 14(1): 6008, 2023 09 28.

Artículo en Inglés | MEDLINE | ID: mdl-37770423

19.

Disorder-function relationships for the cell cycle regulatory proteins p21 and p27.

Mitrea, Diana M; Yoon, Mi-Kyung; Ou, Li; Kriwacki, Richard W.

Biol Chem ; 393(4): 259-74, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-23029651

20.

Cell cycle regulation by the intrinsically disordered proteins p21 and p27.

Yoon, Mi-Kyung; Mitrea, Diana M; Ou, Li; Kriwacki, Richard W.

Biochem Soc Trans ; 40(5): 981-8, 2012 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-22988851

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LAG3 associates with TCR-CD3 complexes and suppresses signaling by driving co-receptor-Lck dissociation.

Coexisting Liquid Phases Underlie Nucleolar Subcompartments.

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.

C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function.

CD-CODE: crowdsourcing condensate database and encyclopedia.

Composition-dependent thermodynamics of intracellular phase separation.

Flipping the switch.

Structural polymorphism in the N-terminal oligomerization domain of NPM1.

Phase separation in biology; functional organization of a higher order.

Asymmetric Modulation of Protein Order-Disorder Transitions by Phosphorylation and Partner Binding.

Broadly protective protein-based pneumococcal vaccine composed of pneumolysin toxoid-CbpA peptide recombinant fusion protein.

Biomolecular Condensates as Novel Antiviral Targets.

Biomolecular condensates form spatially inhomogeneous network fluids.

Biomolecular condensates form spatially inhomogeneous network fluids.

Engineering an artificial zymogen by alternate frame protein folding.

Biomolecular condensates form spatially inhomogeneous network fluids.

Phase Separation in Biology and Disease; Current Perspectives and Open Questions.

Defining the condensate landscape of fusion oncoproteins.

Disorder-function relationships for the cell cycle regulatory proteins p21 and p27.

Cell cycle regulation by the intrinsically disordered proteins p21 and p27.